Jer 50:8 Remove out of the midst of Babylon, and go forth out of the land of the Chaldeans, and be as the he goats before the flocks.
There is some that believe that the "Babylon" of the end times is two different entities. One is physical Babylon which they believe is the USA. The second is spiritual Babylon which is the organized religions and denominations which have descended from the Roman Catholic church. Therefore "remove out of the midst of Babylon" here is referring to getting out of the spiritual Babylon.
Jer 50:9 For, lo, I will raise and cause to come up against Babylon an assembly of great nations from the north country (depending on your location in the US, going straight north over the pole one will come to either Russia or China): and they shall set themselves in array against her; from thence she shall be taken: their arrows (missles) shall be as of a mighty expert man; none shall return in vain.
At one point it seems I saw a map of how Russia had her missles aimed at points in the US and the trajectory of those missles was over the North Pole.
Jer 50:13 Because of the wrath of the LORD (again a phrase associated with end times) it shall not be inhabited, but it shall be wholly desolate: every one that goeth by Babylon shall be astonished, and hiss at all her plagues.
While ancient Babylon was totally devastated and has not been inhabited since, the plagues may reference the US and future biological and post-devastation outbreaks of disease.